The NFL Week 6 injury report for Sunday, October 18, 2026, features several major absences, with Philadelphia Eagles quarterback Jalen Hurts, Baltimore Ravens quarterback Lamar Jackson and Tampa Bay Buccaneers quarterback Baker Mayfield among the players ruled out. Chicago Bears quarterback Caleb Williams, meanwhile, is expected to return against the Atlanta Falcons after missing three games with a hamstring injury.
New York Jets running back Breece Hall, Philadelphia Eagles running back Saquon Barkley and Kansas City Chiefs wide receiver Rashee Rice among those unavailable for Sunday’s games. Several other notable players, including New Orleans Saints running back Alvin Kamara, wide receiver Chris Olave and Buffalo Bills defensive tackle Ed Oliver, are listed as questionable. Their final availability depends on game-day decisions.
NFL Week 6 Injury Updates: Key Players to Watch
Hurts is set to miss at least four games after the Eagles placed him on injured reserve because of a superficial blood clot in his calf. The team said the issue was discovered after he sought treatment following Philadelphia’s Week 4 game against the Los Angeles Rams.
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Tanner McKee is set to start at quarterback against the Carolina Panthers. Barkley is also ruled out with a hamstring injury, adding to Philadelphia’s offensive absences.
Jackson is out for Baltimore’s matchup against the Cleveland Browns with an ankle injury, while Mayfield will miss Tampa Bay’s game against the Pittsburgh Steelers because of a thumb injury.
The Jets will be without Hall because of a quadriceps injury, and the Chiefs will be missing Rice with hamstring and knee issues. These absences could affect several teams’ offensive plans in Week 6.
Chicago has received more encouraging news. Williams is expected to start against Atlanta after practising fully through the week and recovering from the hamstring injury that kept him out for three games.
New England has also activated wide receiver A.J. Brown from injured reserve following a high ankle sprain. Brown is officially listed as questionable, but reports indicate he is expected to play against the Jets.
Pittsburgh wide receiver DK Metcalf has been removed from the injury report after being listed with an illness and is expected to play against Tampa Bay.
NFL Week 6 Injury Report: Expected to Play
Caleb Williams, Chicago Bears: Expected to start against the Falcons after missing three games with a hamstring injury.
A.J. Brown, New England Patriots: Expected to play after being activated from injured reserve, although he remains officially questionable.
DK Metcalf, Pittsburgh Steelers: Removed from the injury report and expected to play after an illness.
Michael Penix Jr., Atlanta Falcons: Listed without a game-status designation on the latest report after a rib injury the previous week.
Patrick Mahomes, Kansas City Chiefs: Listed without an injury designation on the latest report.
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